Large scale filling capacities at BioConnection
Large scale filling line
Automated filling line in “tunnel” design
Filling line (Groninger) | |
---|---|
|
in grade D cleanroom |
|
in grade D cleanroom |
|
grade A open RABS in grade B cleanroom |
|
grade A open RABS in grade D cleanroom |
Lyophilizer (HOF) | grade A open RABS in grade B cleanroom |
---|---|
|
|
|
|
|
Capacity |
---|
|
|
|
|
|
|
EMA and US-FDA certified facility



Large-scale filling line + 10 m² freeze dryer
Compounding volumes: up to 500L+
Indicative maximum batch sizes (*)
Vial size | Liquid product | Freeze dried product |
2 RDIN | 57,000 – 150,000 | 44,900 |
6 RDIN | 57,000 – 150,000 | 23,200 |
10 RDIN | 50,000 – 150,000 | 19,600 |
20 RDIN | 25,000 – 100,000 | 12,600 |
25 RDIN | 20,000 – 80,000 | 12,600 |
50 RDIN | 10,000 – 40,000 | 6,800 |
(*) Actual batch size depends on requested scale of production and filling volume/vial. Examples are based on a 50% filling volume/vial (e.g. 25 ml fill in a 50 RDIN vial, etc.)