Read our expansion updates Expansion update Covid update


We have a wide range of expertise in from small molecules up to advanced products like proteins, vaccins, peptides and antibodies.

Fill and Finish

BioConnection offers clinical and commercial fill and finish for product including liquid fill or lyophilization intended for vials, ampoules, prefilled syringes or blowfill seals.

Finished product

When your product leaves our facility, it needs additional steps to reach the clinic. These steps can also be provided by BioConnection.

Expansion to 50 million vials per year

We are building a brand-new fully automated production line. 

The unique formula

BioConnection offers young and innovative biopharmaceutical companies access to our state-of-the-art-GMP manufacturing facility and a broad range of support services. We are a contract services and manufacturing organization for the development and manufacture (Filling and Freeze drying) of injectable (bio)pharmaceutical products. The Netherlands are located centrally in Europe and from our proprietary site in Oss we supply both clinical as commercial products to our worldwide customers (FDA/EMA). Besides the central location, The Netherlands are also well known for their professional flexibility, organizational savvy and command of foreign languages. Besides our own EMA/FDA approved facility we have access to various facilities across Europe to enable an unmatched flexibility in solutions, capacity and capability. The cornerstones of our CMC services are: Drug Product development, Fill and Finish, Freeze drying and Finished Product services.

Any specific needs?

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Our building blocks to fullfill your needs. You can tailor our services to your specific needs.

GMP manufacturing facility

  • Aseptic filling
  • Freeze drying
  • Terminal sterilization
  • Batch certification
  • EMA and US-FDA track record
  • Automated fill
  • Manual fill, labelling and packaging
  • Batch volume: 2 – 50L
  • Freeze-drier: Shelf surface 1 x 3 m2

Personalised medicine

  • Cell based therapy
  • Microspheres
  • Flexible GMP cleanroom setup

‘One of the very best experiences of tech transfer, development, scale-up and manufacture’

Dr. Peter L. Spargo

Senior Vice President, Chemistry, Manufacturing & Controls, Verona Pharma plc

In early 2016, we at Verona Pharma were looking for a CMO to support the manufacture of clinical trial batches of our lead product RPL554 (ensifentrine), a first-in-class inhaled agent under development for the treatment of respiratory diseases with significant unmet medical needs such as chronic obstructive pulmonary disease (COPD), asthma and cystic fibrosis.


As a growing company, we regularly have new opportunities. As these will not always be posted online, we invite you to send us your resume in case you want to join our enthusiastic team. Please send your motivation letter to


Why choose BioConnection?

We solve your challenges

Any API you need

“We provide solutions, creativity and solve challenges for your product. And yes, we also reliably provide top notch fill and finish for you from clinics to market.”

[Alexander Willemse – CEO]

Covid-19 update BioConnection

BioConnection has taken precautions related to the global outbreak of the Covid-19 virus. To start with; we are currently in full operation and running on-schedule with regard to our planned productions. Our production department is on full strength and we have no shortages of material(s) nor do we foresee them.

For our personnel we are following the guidelines as issued by the Dutch National Institute for Public Health and the Environment, RIVM ( This means that people stay at home when they show (early) symptoms connected to Covid-19. Furthermore BioConnection employees work from home as much as possible. We avoid shaking hands and keep distance from each other. We take every precaution as advised to prevent the spread of the Covid-19 virus and will fully comply to the requests as stated and/or enforced by the authorities.

Our expansion project ( is running as planned to start GMP production in Q2 2021. We stay in close contact with our suppliers for the production equipment.

We review for Covid policy changes by the authorities on a daily base and adapt to them. If changes occur, this statement will be updated accordingly so you always have the latest information. In case you have any questions, please do not hesitate to contact us via our general number or website. Current customers of BioConnection, can contact their dedicated program manager. In case you want BioConnection to become a partner in your development or manufacturing, please contact our Business Development department via

The BioConnection Management Team.

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